Upper Mississippi River Cruises

Early explorers and native tribes left their legacy behind in town names here: Joliet. Red Wing. Dubuque. Rolling farmland stretches out to the horizon; barges are measured in acres; man-made lakes and locks channel the river’s flow. What to do on a river day? Grab your binoculars and study a pair of American bald eagles. Wave to the motorboat captains locking through the dam beside you. Study red in ten different shades of fall foliage. Tap into the sense of wonder that caused early pioneers to call the heartland home.  

Mississippi river cruise itineraries handpicked to pique the interest of nature lovers, history buffs and culture enthusiasts let you delve into beauty and adventure on an epic scale. After all, this is America’s Heartland, envisioned by Washington and Jefferson, celebrated by Mark Twain and stitched into the very fabric of a nation. From Chippewa country in the north to the confluence of the Missouri near St. Louis and Ohio Rivers at Cairo, the Upper Mississippi flows through the pages of U.S. history.

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(16) Upper Mississippi River Cruises Available

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9 day mississippi river cruise from st. paul
Jul 23 - Jul 31

Alton (St. Louis) to Red Wing (Minneapolis)

Mark Twain

AN AMERICAN LITERARY ICON – Many would argue that Samuel Clemens, best known by his pen name Mark Twain, is quite simply one of America's greatest authors. On this magnificent journey along the Upper Mississippi River, you will delve...

Duration
9 Days
Fares from
$1,799
Jul 30 - Aug 07

Roundtrip Red Wing (Minneapolis)

Life on the Mississippi

THE AMERICAN SPIRIT THRIVES – This is a timeless voyage that allows you to travel the Upper Mississippi region - an area rich with frontier tales of fur traders and pioneers set among picturesque geography and abundant wildlife. Twain's...

Duration
9 Days
Fares from
$1,799
Aug 06 - Aug 14

Roundtrip Red Wing (Minneapolis)

The 50s and 60s Remembered

A VOYAGE TO REMEMBER - Let the musical sounds of the 50s and 60s whisk you away on this nostalgic journey through America's historic heartland. Dance and sing the nights away and fill your days with cultural exploration on this...

Duration
9 Days
Fares from
$1,799
Mississippi River Cruise ship
Aug 13 - Sep 04

Red Wing (Minneapolis) to New Orleans

The Mighty Mississippi

AUTHENTIC AMERICA ON THE MIGHTY MISSISSIPPI - Have you ever wondered what this country looked like to its early explorers and pioneers? Traveling on the Mississippi and its tributaries aboard the elegant American Queen, you will be...

Duration
23 Days
Fares from
$4,899
mississippi river cruise from st. paul to st. louis
Sep 03 - Sep 11

Red Wing (Minneapolis) to St. Louis

Mark Twain

AN AMERICAN LITERARY ICON – Many would argue that Samuel Clemens, best known by his pen name Mark Twain, is quite simply one of America's greatest authors. On this magnificent journey along the Upper Mississippi River, you will delve...

Duration
9 Days
Fares from
$2,699
Sep 10 - Sep 18

St. Louis to Memphis

Civil War

THE ENDURING LEGACY OF THE CIVIL WAR - The Mississippi River was of great strategic value as both a transportation and communication route during the Civil War. Experience authentic Southern culture as you journey through living history and...

Duration
9 Days
Fares from
$2,699
9 day mississippi river cruise from st. paul
Jul 29 - Aug 06

Alton (St. Louis) to Red Wing (Minneapolis)

Life on the Mississippi

THE AMERICAN SPIRIT THRIVES – This is a timeless voyage that allows you to travel the Upper Mississippi region - an area rich with frontier tales of fur traders and pioneers set among picturesque geography and abundant wildlife. Twain's...

Duration
9 Days
Fares from
$1,999
Aug 05 - Aug 20

Red Wing (Minneapolis) to New Orleans

The Mighty Mississippi

AUTHENTIC AMERICA ON THE MIGHTY MISSISSIPPI - Have you ever wondered what this country looked like to its early explorers and pioneers? Traveling on the Mississippi and its tributaries aboard the elegant American Queen, you will be...

Duration
16 Days
Fares from
$3,599
mississippi river cruise from st. paul to st. louis
Aug 05 - Aug 13

Red Wing (Minneapolis) to St. Louis

FALL IN LOVE WITH THE HEARTLAND – The upper reaches of the Mississippi River are rich with frontier tales of fur traders and pioneers set among picturesque geography and abundant wildlife. The region reflects the spirit of the people who...

Duration
9 Days
Fares from
$2,799
9 day mississippi river cruise from st.louis
Aug 12 - Aug 20

St. Louis to Ottawa (Chicago)

LINCOLN'S ILLINOIS - Set off on an amazing journey from the famed Gateway Arch in St. Louis to the soaring skyline of Chicago. As you cruise along the Illinois River you will be treated to some of the most beautiful scenery while...

Duration
9 Days
Fares from
$2,799
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