Upper Mississippi River Cruises

Discover America with an Upper Mississippi River Cruise


Early explorers and native tribes left their legacy behind in town names here: Joliet. Red Wing. Dubuque. Rolling farmland stretches out to the horizon; barges are measured in acres; man-made lakes and locks channel the river’s flow. What to do on a river day? Grab your binoculars and study a pair of American bald eagles. Wave to the motorboat captains locking through the dam beside you. Study red in ten different shades of fall foliage. Tap into the sense of wonder that caused early pioneers to call the heartland home.  

Mississippi river cruise itineraries are handpicked to pique the interest of nature lovers, history buffs and culture enthusiasts let you delve into beauty and adventure on an epic scale. After all, this is America’s Heartland, envisioned by Washington and Jefferson, celebrated by Mark Twain and stitched into the very fabric of a nation. From Chippewa country in the north to the confluence of the Missouri near St. Louis and Ohio Rivers at Cairo, the Upper Mississippi flows through the pages of U.S. history.

See the very best of the Upper Mississippi when you travel by paddlewheel river boat on one of our luxury river cruises. Nature buffs, history enthusiasts, culture lovers will all find inspiration and adventure during our cruises, specially planned and designed to give you the ultimate river experience. Discover America’s Heartland, see what Mark Twain wrote about, explore Chippewa country and have a vacation unlike any other. Plan your riverboat cruise along the Upper Mississippi today.

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(10) Upper Mississippi River Cruises Available

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9 day mississippi river cruise from st. paul
Jul 29 - Aug 06

Alton (St. Louis) to Red Wing (Minneapolis)

Life on the Mississippi

THE AMERICAN SPIRIT THRIVES – This is a timeless voyage that allows you to travel the Upper Mississippi region - an area rich with frontier tales of fur traders and pioneers set among picturesque geography and abundant wildlife. Twain's...

Duration
9 Days
Fares from
$1,999
mississippi river cruise from st. paul to st. louis
Aug 05 - Aug 13

Red Wing (Minneapolis) to St. Louis

FALL IN LOVE WITH THE HEARTLAND – The upper reaches of the Mississippi River are rich with frontier tales of fur traders and pioneers set among picturesque geography and abundant wildlife. The region reflects the spirit of the people who...

Duration
9 Days
Fares from
$2,799
Aug 05 - Aug 20

Red Wing (Minneapolis) to New Orleans

The Mighty Mississippi

AUTHENTIC AMERICA ON THE MIGHTY MISSISSIPPI - Have you ever wondered what this country looked like to its early explorers and pioneers? Traveling on the Mississippi and its tributaries aboard the elegant American Queen, you will be...

Duration
16 Days
Fares from
$3,599
9 day mississippi river cruise from st.louis
Aug 12 - Aug 20

St. Louis to Ottawa (Chicago)

LINCOLN'S ILLINOIS - Set off on an amazing journey from the famed Gateway Arch in St. Louis to the soaring skyline of Chicago. As you cruise along the Illinois River you will be treated to some of the most beautiful scenery while...

Duration
9 Days
Fares from
$2,799
Aug 19 - Aug 27

Ottawa (Chicago) to St. Louis

FALL IN LOVE WITH THE HEARTLAND - Set off on an amazing journey from the backdrop of Chicago's soaring skyline to the famed Gateway Arch in bustling St. Louis. As you cruise along the Illinois River you will be treated to some of the...

Duration
9 Days
Fares from
$2,799
gateway arch on a mississippi river cruise
Aug 26 - Sep 03

St. Louis to Red Wing (Minneapolis)

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a journey through America’s Heartland than lively St. Louis, “ The Gateway City.” Theme: • America's Heartland*   Included...

Duration
9 Days
Fares from
$2,799
Sep 02 - Sep 17

Red Wing (Minneapolis) to New Orleans

The Mighty Mississippi

AUTHENTIC AMERICA ON THE MIGHTY MISSISSIPPI - Have you ever wondered what this country looked like to its early explorers and pioneers? Traveling on the Mississippi and its tributaries aboard the elegant American Queen, you will be...

Duration
16 Days
Fares from
$4,999
Sep 09 - Sep 17

Roundtrip Red Wing (Minneapolis)

Heartland Heritage

THE AMERICAN SPIRIT THRIVES – This is a timeless voyage that allows passengers to experience the heartland of America traveling the Upper Mississippi River on a beautiful roundtrip voyage from beautiful Minneapolis - an area rich with...

Duration
9 Days
Fares from
$1,999
Sep 16 - Sep 24

Red Wing (Minneapolis) to Alton (St. Louis)

Mark Twain

AN AMERICAN LITERARY ICON – Many would argue that Samuel Clemens, best known by his pen name Mark Twain, is quite simply one of America's greatest authors. On this magnificent journey along the Upper Mississippi River, you will delve...

Duration
9 Days
Fares from
$1,999
Sep 23 - Oct 01

Alton (St. Louis) to Memphis

The 50s and 60s Remembered

A VOYAGE TO REMEMBER - Let the musical sounds of the 50s and 60s whisk you away on this nostalgic journey through America's historic heartland. Dance and sing the nights away and fill your days with cultural exploration on this...

Duration
9 Days
Fares from
$1,999
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