Upper Mississippi Cruises

Early explorers and native tribes left their legacy behind in town names here: Joliet. Red Wing. Dubuque. Rolling farmland stretches out to the horizon; barges are measured in acres; man-made lakes and locks channel the river’s flow. What to do on a river day? Grab your binoculars and study a pair of American bald eagles. Wave to the motorboat captains locking through the dam beside you. Study red in ten different shades of fall foliage. Tap into the sense of wonder that caused early pioneers to call the heartland home.  

River cruise destinations handpicked to pique the interest of nature lovers, history buffs and culture enthusiasts let you delve into beauty and adventure on an epic scale. After all, this is America’s Heartland, envisioned by Washington and Jefferson, celebrated by Mark Twain and stitched into the very fabric of a nation. From Chippewa country in the north to the confluence of the Missouri near St. Louis and Ohio Rivers at Cairo, the Upper Mississippi flows through the pages of U.S. history.

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(19) Results

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Aug 29 - Sep 06

St. Louis (Alton, IL) to St. Paul

Good Old Summertime

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a journey through America’s Heartland than lively St. Louis, “ The Gateway City.” Theme: • Good Old Summertime Included...

Duration
9 Days
Fares from
$3,599
Sep 05 - Sep 13

St. Paul (Red Wing, MN) to St. Louis (Alton, IL)

Big Band Swing

THE AMERICAN SPIRIT THRIVES – Get "in the mood" for a timeless voyage from the scenic bluffs of Red Wing to St. Louis’ bustling Union Station marketplace. This sentimental journey through America's Heartland features...

Duration
9 Days
Fares from
$3,599
Sep 12 - Sep 20

St. Louis (Alton, IL) to St. Paul

Big Band Swing

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a voyage through America’s Heartland than lively St. Louis, “ The Gateway City.” This sentimental journey features special onboard guest...

Duration
9 Days
Fares from
$3,599
Sep 19 - Sep 27

St. Paul to St. Louis (Alton, IL)

Fall Colors

THE AMERICAN SPIRIT THRIVES – A timeless voyage from the scenic bluffs of Red Wing to St. Louis’ bustling Union Station marketplace. Theme: • Fall Colors Included Tours: • See ports of call below for...

Duration
9 Days
Fares from
$3,599
Sep 26 - Oct 04

St. Louis (Alton, IL) to St. Paul

Fall Colors

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a journey through America’s Heartland than lively St. Louis, “ The Gateway City.” Theme: • Fall Colors Included Tours: • See...

Duration
9 Days
Fares from
$3,599
Oct 03 - Oct 11

St. Paul to St. Louis (Alton, IL)

Oktoberfest

THE AMERICAN SPIRIT THRIVES – This timeless voyage from the scenic bluffs of Red Wing to St. Louis’ bustling Union Station marketplace celebrates Oktoberfest and the best of German style beers from the breweries of America's...

Duration
9 Days
Fares from
$3,599
Oct 10 - Oct 18

St. Louis (Alton, IL) to Nashville (Clarksville, TN)

Fall Colors

A TAPESTRY OF COLOR - Enjoy nature’s handiwork as the leaves display a myriad of colors. Your journey will take you from the plains of St. Louis through the Tennessee hills surrounding Nashville. Theme: • Fall...

Duration
9 Days
Fares from
$2,699
Jul 03 - Jul 11

Memphis to St. Louis (Alton)

Fourth of July Celebration

UNIQUELY AMERICAN CRUISING - Every American Queen Steamboat Company river cruise is a celebration of America, but the chance to spend Independence Day in the American Queen's home port of Memphis is a rare treat. Experience plenty of fanfare...

Duration
9 Days
Fares from
$2,149
Jul 24 - Aug 01

St. Louis (Alton) to St. Paul (Red Wing)

Life on the Mississippi

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a journey through America’s Heartland than lively St. Louis, “ The Gateway City.” Theme: • Life on the Mississippi   Included...

Duration
9 Days
Fares from
$2,149
Jul 31 - Aug 08

St. Paul (Red Wing) to St. Louis (Alton)

Mark Twain

THE AMERICAN SPIRIT THRIVES – A timeless voyage from the scenic bluffs of Red Wing to St. Louis’ bustling Union Station marketplace. Theme: • Mark Twain Included Tours: • See ports of call below for information...

Duration
9 Days
Fares from
$2,249
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