Upper Mississippi Cruises

Early explorers and native tribes left their legacy behind in town names here: Joliet. Red Wing. Dubuque. Rolling farmland stretches out to the horizon; barges are measured in acres; man-made lakes and locks channel the river’s flow. What to do on a river day? Grab your binoculars and study a pair of American bald eagles. Wave to the motorboat captains locking through the dam beside you. Study red in ten different shades of fall foliage. Tap into the sense of wonder that caused early pioneers to call the heartland home.  

River cruise destinations handpicked to pique the interest of nature lovers, history buffs and culture enthusiasts let you delve into beauty and adventure on an epic scale. After all, this is America’s Heartland, envisioned by Washington and Jefferson, celebrated by Mark Twain and stitched into the very fabric of a nation. From Chippewa country in the north to the confluence of the Missouri near St. Louis and Ohio Rivers at Cairo, the Upper Mississippi flows through the pages of U.S. history.

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(26) Results

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Jul 11 - Jul 19

Cincinnati to St. Louis (Alton, IL)

Good Old Summertime

JOURNEY THROUGH THE HEARTLAND - America’s rivers are its natural highways, and the perfect avenue to explore the interior United States. You will truly savor each moment of this leisurely cruise through America’s Heartland. Quaint...

Duration
9 Days
Fares from
$2,699
Jul 18 - Jul 26

St. Louis (Alton, IL) to St. Paul

Good Old Summertime

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a journey through America’s Heartland than lively St. Louis, “ The Gateway City.” Theme: • Good Old Summertime   Included...

Duration
9 Days
Fares from
$3,599
Jul 25 - Aug 02

St. Paul to St. Louis (Alton, IL)

Good Old Summertime

THE AMERICAN SPIRIT THRIVES – A timeless voyage from the scenic bluffs of Red Wing to St. Louis’ bustling Union Station marketplace. Theme: • Good Old Summertime Included Tours: • See ports of call below for...

Duration
9 Days
Fares from
$3,599
Aug 01 - Aug 09

St. Louis (Alton, IL) to St. Paul

Good Old Summertime

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a journey through America’s Heartland than lively St. Louis, “ The Gateway City.” Theme: • Good Old Summertime Included...

Duration
9 Days
Fares from
$2,699
Aug 08 - Aug 16

Roundtrip St. Paul

Music of the 50s and 60s

SHAKE, RATTLE AND ROLLIN’ ON THE RIVER - Join us on a nostalgic journey to the fun-loving, carefree days of the 50s and 60s as we re-create the music, activities and events of this golden era. You’ll rock around the clock to the...

Duration
9 Days
Fares from
$2,699
Aug 15 - Aug 23

St. Paul to St. Louis (Alton, IL)

Good Old Summertime

THE AMERICAN SPIRIT THRIVES – A timeless voyage from the scenic bluffs of Red Wing to St. Louis’ bustling Union Station marketplace. Theme: • Good Old Summertime Included Tours: • See ports of call below for...

Duration
9 Days
Fares from
$2,699
Aug 22 - Aug 30

Roundtrip St. Louis (Alton, IL)

Mark Twain

MARK TWAIN’S MISSISSIPPI RIVER - Visit Mark Twain’s hometown of Hannibal, Missouri from where much of his inspiration for his stories of Tom Sawyer and Huckleberry Finn is derived. Witness his words and wit brought to life by expert...

Duration
9 Days
Fares from
$2,699
Aug 29 - Sep 06

St. Louis (Alton, IL) to St. Paul

Good Old Summertime

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a journey through America’s Heartland than lively St. Louis, “ The Gateway City.” Theme: • Good Old Summertime Included...

Duration
9 Days
Fares from
$3,599
Sep 05 - Sep 13

St. Paul (Red Wing, MN) to St. Louis (Alton, IL)

Big Band Swing

THE AMERICAN SPIRIT THRIVES – Get "in the mood" for a timeless voyage from the scenic bluffs of Red Wing to St. Louis’ bustling Union Station marketplace. This sentimental journey through America's Heartland features...

Duration
9 Days
Fares from
$3,599
Sep 12 - Sep 20

St. Louis (Alton, IL) to St. Paul

Big Band Swing

FALL IN LOVE WITH THE HEARTLAND – There’s no better place to begin a voyage through America’s Heartland than lively St. Louis, “ The Gateway City.” This sentimental journey features special onboard guest...

Duration
9 Days
Fares from
$3,599
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